pd-1/pd-l1 inhibitor 1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3655	BMS-1	PD1-PDL1 inhibitor 1,PD-1/PD-L1 inhibitor 1	Apoptosis , PD-1/PD-L1
	BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene ...		Apoptosis , PD-1/PD-L1
T9616	PD-1/PD-L1-IN-10		PD-1/PD-L1
	PD-1/PD-L1-IN-10 is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy.		PD-1/PD-L1
T3146	BMS-202	PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2	Apoptosis , PD-1/PD-L1
	BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.		Apoptosis , PD-1/PD-L1
T4696	BMS202 hydrochloride (1675203-84-5(free base))	PD-1/PD-L1 inhibitor 2 hydrochloride	PD-1/PD-L1
	BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L...		PD-1/PD-L1
T26859	BMS-8		PD-1/PD-L1
	BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.		PD-1/PD-L1
T39591	Human PD-L1 inhibitor I	Human PD-L1 inhibitor I
	Human PD-L1 inhibitor I is a peptide ligand that specifically inhibits the interaction between human PD-L1 and human PD-1. It exhibits a KD value of 3.39 μM, indicating its binding affinity. The presence of Human PD-L1 i...
T39588	Human PD-L1 inhibitor IV	Human PD-L1 inhibitor IV
	Human PD-L1 inhibitor IV is a polypeptide compound that competitively inhibits the human PD-1 protein. It has a Kd value of 1.38 μM and effectively blocks the interaction between hPD-1 and hPD-L1.
T39589	Human PD-L1 inhibitor III	Human PD-L1 inhibitor III
	Human PD-L1 inhibitor III is a human PD-L1 inhibitor.
T39590	Human PD-L1 inhibitor II	Human PD-L1 inhibitor II
	Human PD-L1 inhibitor II is a potent PD-L1 inhibitor with anti-cancer activity.
T36899	INCB086550	PD-1/PD-L1-IN-8	PD-1/PD-L1
	INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.		PD-1/PD-L1
T36487	Evixapodlin	PD-1/PD-L1-IN 7,GS-4224	Antiviral , HBV , PD-1/PD-L1
	Evixapodlin (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor (IC50: 0.213).Evixapodlin has anticancer and antiviral activities.		Antiviral , HBV , PD-1/PD-L1
T83976	ARB-272572 hydrochloride	ARB-272572 hydrochloride（2368182-63-0 Free base）	PD-1/PD-L1
	ARB-272572 hydrochloride is a small molecule PD-L1 inhibitor with an IC50 value of 400 pM for PD-1/PD-L1 HTRF.ARB-272572 hydrochloride inhibits PD-1/PD-L1 cell signaling by inducing homologous interactions with PD-L1 pro...		PD-1/PD-L1
T5697	BMS-1166		PD-1/PD-L1
	BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.		PD-1/PD-L1
T9651	PD-1/PD-L1-IN-9		PD-1/PD-L1
	PD-1/PD-L1-IN-9, with an IC50 of 3.8 nM, is a potent and orally active inhibitor of the PD-1/PD-L1 interaction. It enhances the immune cells' ability to kill tumor cells and demonstrates significant antitumor activity in...		PD-1/PD-L1
T12379	PD-1-IN-22		Others , PD-1/PD-L1
	PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).		Others , PD-1/PD-L1
T10565	BMS-1001 hydrochloride		PD-1/PD-L1
	BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activat...		PD-1/PD-L1
T8470	BMS-1001		PD-1/PD-L1
	BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).		PD-1/PD-L1
T40111L	BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride		PD-1/PD-L1
	BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor that inhibits the PD-1/PD-L1 interaction wi...		PD-1/PD-L1
T76750	Cemiplimab	REGN-2810,SAR-439684	Others
	Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cance...		Others
T3468	Tomivosertib	eFT508	MNK , PD-1/PD-L1
	Tomivosertib (eFT508) is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.		MNK , PD-1/PD-L1